Ua kūpaʻa ʻo Smart Weigh i ke kōkua ʻana i nā mea kūʻai aku e hoʻonui i ka huahana ma ke kumukūʻai hoʻemi.
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Ua kūpaʻa ʻo Smart Weigh i ke kōkua ʻana i nā mea kūʻai aku e hoʻonui i ka huahana ma ke kumukūʻai hoʻemi.
Mea kākau: Smartweigh–Mea Kaumaha Poʻo Nui
ʻEhā mau koho aseptic packaging e noʻonoʻo ai. I kēia mau lā, ʻo nā ʻenehana like ʻole e ʻimi ana i nā mea hana lāʻau lapaʻau a me biopharmaceutical: (1) piha piha 100 lumi maʻemaʻe, (2) nā mea hoʻokaʻawale, (3) nā ʻōnaehana hoʻopaʻa ʻia (RABS), (4) nā ʻōnaehana hoʻohana hoʻokahi. ʻO wai ka mea maikaʻi iā ʻoe? 1. Papa 100 lumi maʻemaʻe: Ua hoʻomohala mua ʻia ka ʻenehana lumi maʻemaʻe i ka makahiki 1960 no ka hoʻohana ʻana i ka ʻoihana aerospace a me nā ʻoihana uila e pale aku i ka hoʻohaumia ʻana o nā ʻāpana liʻiliʻi.
He mau ʻāpana bacteria, a ua ʻike koke ka ʻoihana lāʻau lapaʻau e hiki i kēia mākaukau ke hōʻoia i ka ea sterile. aleksandarlittlewolf - www.freepik.comPharma-gowning-young-technologist-putting-protective-rubber-gloves-production-factory-freepik-web.jpg ʻO nā lumi maʻemaʻe papa 100 ka mea maʻamau i ka hana aseptic (ISO 5 a me A/B Class performance ua like), me ka hoʻohana ʻana i kahi kānana particulate air kiʻekiʻe (HEPA) e wehe i nā ʻāpana a me nā maʻi bacteria. ʻO ka nui o ka laminar a i ʻole ka holo ʻana o ka ea unidirectional e hōʻemi i ka hoʻoili ʻana o nā ʻāpana mai kahi wahi a i kekahi.
I ka makahiki 1970, ua hana ʻia ka hoʻopiha aseptic ma nā mīkini kikoʻī ma lalo o nā panela kānana HEPA. ʻO nā ʻāpana mīkini ma luna o ka ipu ke kumu o ka haumia, a i ka wā lōʻihi e neʻe ʻia lākou ma lalo o ka pae hana. No ka ʻoi aku ka maikaʻi o ka ea kānana ma ka mīkini, ua hoʻohui pū ʻia nā uhi puka aniani.
Hoʻomanaʻo pū ka lole puka makani i ka mea hoʻohana e pale aku i ka hoʻopā ʻana i ka mīkini a huahana paha. Huli nā mea hana i 100% HEPA pāpaku e hoʻomalu i nā lumi holoʻokoʻa i ka papa 100. Hoʻomaikaʻi kēia i ka mana, akā hoʻonui i ke kumukūʻai a me nā kumukūʻai hana, ʻoi aku ka ʻōnaehana mālama ea.
2. Opto-Isolators: Ma nā makahiki 80 a me 90, ua hoʻomohala ʻia nā mea hoʻokaʻawale e hoʻomaikaʻi i ka pale ma waena o nā kānaka a me nā huahana ʻoiai e hōʻemi ana i nā kumukūʻai. Hōʻike ʻia ka mea hoʻokaʻawale ma ke ʻano he lumi maʻemaʻe i loko o kahi pahu. Hoʻopili ʻia ke kaʻina holoʻokoʻa i loko o kahi keʻena i hoʻopaʻa ʻia, kaomi ʻia me ka ea i kānana ʻia e nā kānana HEPA.
I ka wā o ka hana, ʻaʻole ʻae ʻia ka mea hoʻohana e komo ke ʻole ma o ke kikowaena mīkina lima. Na ke kiʻi na chase-logeman anchaselogeman-isolator-web.jpg no ka ʻōnaehana kaʻawale (ʻaʻole i hōʻike ʻia ke kānana HEPA luna). Hoʻomaikaʻi ʻia ke kiʻi na chase-logeman anchase-logman-isolator-inside-web.jpg hānai i ka mea hoʻokaʻawale i loko e hōʻike ana i ke awa mīkina lima.
Ma hope o ka holo ʻana, e wehe ʻia ka mea hoʻokaʻawale, hoʻomaʻemaʻe, a mākaukau no ka holo aʻe. Ke hoʻopaʻa hou ʻia, hoʻopiha ʻia ka mea hoʻokaʻawale me kahi sterilant, maʻamau vapor hydrogen peroxide (VHP), e hoʻomaʻemaʻe i nā mea āpau i loko. ʻAʻole like me ka hoʻoheheʻe kuʻuna a i ʻole ka disinfection scrub, komo ʻo VHP i nā ʻāpana liʻiliʻi loa.
Ma hope o ka sterilized, hana ʻia kekahi hoʻonohonoho hope ma o ke awa mīkina lima. Ma ke kumumanaʻo, pono e hiki ke hana i ka mea hoʻokaʻawale ma kahi ākea ʻole, e like me kahi hale kūʻai, e kahi mea hoʻohana e ʻaʻahu ana i ka lole lab. Theoretically ʻo ia.
ʻO ka ʻoiaʻiʻo, ua hoʻokomo nā hui he nui i nā mea hoʻokaʻawale i ka papa 100 lumi maʻemaʻe. Hāʻawi kēia i kahi papa hoʻomaʻemaʻe ʻē aʻe, akā ʻo ka waiwai ke kūkulu i kahi mea hoʻokaʻawale e pale aku ai. 3. Pūnaehana Paʻa Paʻa Loaʻa (RABS): He kuʻikahi ka RABS ma waena o kahi ʻōnaehana hāmama a me kahi ʻōnaehana kaʻawale, aia ka RABS i ke kaʻina hana i loko o kahi pā paʻa.
Komo nā hana hana ma ke awa mīkina lima. ʻO Syntegon Pharma technologies Syntegon-Pharma- products_filling and Closing_FXS_3100-web.jpg Hoʻonui ka RABS hāmama i ke kaupaku, e hilinaʻi ana i ka mālama ʻana i ka ea a me ka ʻōnaehana kānana. Loaʻa i ka RABS i pani ʻia i kāna ʻōnaehana ea a me kāna ʻōnaehana kānana.
Loaʻa i ka RABS nā kumu kūʻai nui ma mua o nā mea hoʻokaʻawale ma muli o kona maʻalahi. He ʻoiaʻiʻo kēia inā hiki ke loaʻa i loko o nā lumi hoʻomaʻemaʻe e kū nei a laila hoʻemi i nā kumukūʻai kūkulu. ʻO ka pono e kūkulu i kahi lumi maʻemaʻe e hoʻopau i kekahi o nā kumukūʻai e hoʻohālikelike ʻia me nā mea hoʻokaʻawale.
4. Pūnaehana hoʻokuʻu: Ke lilo nei nā ʻōnaehana lawelawe ʻana i nā huahana hoʻopau a kaulana loa i nā noi aseptic. Aia i loko o kēia mau ʻōnaehana kahi ʻeke plastik e pani ai i ke kini metala maʻamau. Hoʻopili mua ʻia ka ʻeke me nā kānana āpau, nā paipu, nā awa, nā nozzles hoʻopiha, a me nā mea pono ʻē aʻe.
Hoʻopaʻa ʻia i loko o kahi ʻeke pale a sterilized. Hoʻopiha ka mea hana hana i ka ʻōnaehana sterile a mākaukau no ka hana. Kiʻi mahalo ʻia e sartorioussaritus Img_OctoPlus-_4154-web.jpg Hāʻawi kekahi mau mea hana i nā ʻōnaehana hoʻohana hoʻokahi maʻamau, me Sartorius (kona PreVAS - pre-validated, pre-assembled, pre-sterilized - Project Syntegon), Pall Corporation (kona Biotech hoʻokahi hoʻohana ʻana i ka moekolohe. Pūnaehana) etc.
Wahi a Marion Monstier, Sartorius Freeze-Thaw Products Manager, ʻo nā mea maikaʻi o nā ʻōnaehana hoʻohana hoʻokahi: • ʻO nā ʻōnaehana pani ʻia e hōʻemi i ka hoʻoili ʻana a me ka mālama ʻana i nā huahana, e hōʻemi ana i ka hopena o ka haumia. • ʻO ka hoʻololi ʻana i nā ʻōnaehana hoʻohana hoʻokahi ma waena o nā holo huahana e hoʻopau i ka hiki ke hoʻopaʻa ʻia ma muli o ka hoʻomaʻemaʻe ʻole a i ʻole ka hoʻomaʻemaʻe pono ʻole. • Hoʻohālikelike i nā ʻōnaehana hiki ke hoʻohana hou ʻia, hoʻemi kēia mau ʻōnaehana ʻokoʻa i ka hoʻololi a me ka manawa hoʻonohonoho.
• Hoʻopau lākou i nā koi hōʻoia hoʻomaʻemaʻe. • 'Oi aku ka maika'i o ka wai, a laila e ho'onui ai i ka ho'iho'i hou 'ana i ka huahana.
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